Query results for "SH2":


SH2(hide)

HMM profile interface residues in SH2 binding partner(s)
residues 1-3 of SH2 are in the interface residues 4-6 of SH2 are in the interface residues 7-8 of SH2 are in the interface residues 9-9 of SH2 are in the interface residues 10-10 of SH2 are in the interface residues 12-12 of SH2 are in the interface residues 13-14 of SH2 are in the interface residues 16-16 of SH2 are in the interface residues 17-17 of SH2 are in the interface residues 18-18 of SH2 are in the interface residues 19-19 of SH2 are in the interface residues 20-20 of SH2 are in the interface residues 23-25 of SH2 are in the interface residues 28-28 of SH2 are in the interface residues 30-30 of SH2 are in the interface residues 31-31 of SH2 are in the interface residues 33-34 of SH2 are in the interface residues 43-44 of SH2 are in the interface residues 45-46 of SH2 are in the interface
Pkinase_Tyr DDI of SH2 and Pkinase_Tyr, SH2 DDI of SH2 and SH2
residues 1-2 of SH2 are in the interface residues 3-4 of SH2 are in the interface residues 24-24 of SH2 are in the interface residues 26-26 of SH2 are in the interface residues 33-34 of SH2 are in the interface residues 71-71 of SH2 are in the interface residues 74-74 of SH2 are in the interface
SOCS_box DDI of SH2 and SOCS_box, SH2 DDI of SH2 and SH2
residues 1-1 of SH2 are in the interface residues 12-13 of SH2 are in the interface residues 16-16 of SH2 are in the interface residues 17-18 of SH2 are in the interface residues 19-21 of SH2 are in the interface residues 41-41 of SH2 are in the interface residues 43-43 of SH2 are in the interface residues 45-45 of SH2 are in the interface residues 74-75 of SH2 are in the interface residues 77-77 of SH2 are in the interface
SH3_1 DDI of SH2 and SH3_1, Pkinase_Tyr DDI of SH2 and Pkinase_Tyr, SH2 DDI of SH2 and SH2
residues 1-1 of SH2 are in the interface residues 2-2 of SH2 are in the interface residues 3-4 of SH2 are in the interface residues 5-5 of SH2 are in the interface residues 6-6 of SH2 are in the interface residues 7-10 of SH2 are in the interface residues 12-13 of SH2 are in the interface residues 21-22 of SH2 are in the interface residues 24-24 of SH2 are in the interface residues 26-27 of SH2 are in the interface residues 28-28 of SH2 are in the interface residues 29-29 of SH2 are in the interface residues 30-30 of SH2 are in the interface residues 31-32 of SH2 are in the interface residues 33-35 of SH2 are in the interface residues 36-36 of SH2 are in the interface residues 37-38 of SH2 are in the interface residues 40-40 of SH2 are in the interface residues 42-42 of SH2 are in the interface residues 47-51 of SH2 are in the interface residues 52-53 of SH2 are in the interface residues 54-54 of SH2 are in the interface residues 55-56 of SH2 are in the interface residues 57-57 of SH2 are in the interface residues 58-58 of SH2 are in the interface residues 59-59 of SH2 are in the interface residues 60-60 of SH2 are in the interface residues 61-61 of SH2 are in the interface residues 62-63 of SH2 are in the interface residues 64-64 of SH2 are in the interface residues 65-66 of SH2 are in the interface residues 67-67 of SH2 are in the interface residues 68-72 of SH2 are in the interface residues 73-73 of SH2 are in the interface residues 74-74 of SH2 are in the interface residues 75-75 of SH2 are in the interface residues 76-77 of SH2 are in the interface
SH3_1 DDI of SH2 and SH3_1, Pkinase_Tyr DDI of SH2 and Pkinase_Tyr, SH2 DDI of SH2 and SH2
residues 2-2 of SH2 are in the interface residues 3-4 of SH2 are in the interface residues 5-5 of SH2 are in the interface residues 6-6 of SH2 are in the interface residues 7-8 of SH2 are in the interface residues 9-11 of SH2 are in the interface residues 27-27 of SH2 are in the interface residues 28-35 of SH2 are in the interface residues 36-37 of SH2 are in the interface residues 45-46 of SH2 are in the interface residues 47-48 of SH2 are in the interface residues 49-49 of SH2 are in the interface residues 50-50 of SH2 are in the interface residues 51-52 of SH2 are in the interface residues 53-53 of SH2 are in the interface residues 54-55 of SH2 are in the interface residues 56-56 of SH2 are in the interface residues 58-58 of SH2 are in the interface
Pkinase_Tyr DDI of SH2 and Pkinase_Tyr, STAT_bind DDI of SH2 and STAT_bind, SH2 DDI of SH2 and SH2
residues 3-3 of SH2 are in the interface residues 6-6 of SH2 are in the interface residues 11-11 of SH2 are in the interface residues 14-14 of SH2 are in the interface residues 17-19 of SH2 are in the interface residues 77-77 of SH2 are in the interface
STAT_bind DDI of SH2 and STAT_bind
residues 5-5 of SH2 are in the interface residues 30-30 of SH2 are in the interface residues 33-33 of SH2 are in the interface
SH2 DDI of SH2 and SH2
residues 6-6 of SH2 are in the interface residues 7-7 of SH2 are in the interface residues 8-8 of SH2 are in the interface residues 9-9 of SH2 are in the interface residues 12-13 of SH2 are in the interface residues 16-16 of SH2 are in the interface residues 27-27 of SH2 are in the interface residues 28-28 of SH2 are in the interface residues 29-29 of SH2 are in the interface residues 30-31 of SH2 are in the interface residues 32-32 of SH2 are in the interface residues 36-36 of SH2 are in the interface residues 37-37 of SH2 are in the interface residues 38-38 of SH2 are in the interface residues 40-40 of SH2 are in the interface residues 41-41 of SH2 are in the interface residues 42-42 of SH2 are in the interface residues 43-44 of SH2 are in the interface residues 45-45 of SH2 are in the interface residues 46-46 of SH2 are in the interface residues 47-47 of SH2 are in the interface residues 48-48 of SH2 are in the interface residues 49-50 of SH2 are in the interface residues 51-51 of SH2 are in the interface residues 52-52 of SH2 are in the interface residues 54-56 of SH2 are in the interface residues 58-59 of SH2 are in the interface residues 60-60 of SH2 are in the interface residues 61-61 of SH2 are in the interface residues 62-62 of SH2 are in the interface residues 63-64 of SH2 are in the interface residues 65-65 of SH2 are in the interface residues 66-66 of SH2 are in the interface residues 77-77 of SH2 are in the interface
LIG_SH2_STAT5 (Y[VLTFIC].., from ELM) DMI of SH2 and LIG_SH2_STAT5, SH2_LIG_1 (T.YAQ.Q, from PLoS_CB_2010) DMI of SH2 and SH2_LIG_1, LIG_SH2_PTP2 (Y[IV].[VILP], from ELM) DMI of SH2 and LIG_SH2_PTP2, SH3_1 DDI of SH2 and SH3_1, LIG_SH2_STAT3 (Y..Q, from ELM) DMI of SH2 and LIG_SH2_STAT3, SH2_LIG_0 (YVN, from PLoS_CB_2010) DMI of SH2 and SH2_LIG_0, LIG_SH2_none (manually curated) DMI of SH2 and LIG_SH2_none, LIG_SH2_GRB2 (Y.N., from ELM) DMI of SH2 and LIG_SH2_GRB2, LIG_SH2_SRC (Y[QDEVAIL][DENPYHI][IPVGAHS], from ELM) DMI of SH2 and LIG_SH2_SRC
residues 8-8 of SH2 are in the interface residues 44-45 of SH2 are in the interface residues 46-49 of SH2 are in the interface residues 51-51 of SH2 are in the interface residues 58-61 of SH2 are in the interface residues 63-63 of SH2 are in the interface
PI3Ka DDI of SH2 and PI3Ka, fn3 DDI of SH2 and fn3
residues 9-9 of SH2 are in the interface residues 13-13 of SH2 are in the interface
Pkinase_Tyr DDI of SH2 and Pkinase_Tyr
residues 16-17 of SH2 are in the interface residues 42-44 of SH2 are in the interface residues 45-45 of SH2 are in the interface residues 47-48 of SH2 are in the interface
PI3K_C2 DDI of SH2 and PI3K_C2, SH2 DDI of SH2 and SH2
residues 31-32 of SH2 are in the interface residues 33-34 of SH2 are in the interface residues 50-50 of SH2 are in the interface residues 52-52 of SH2 are in the interface residues 60-60 of SH2 are in the interface
SH3_1 DDI of SH2 and SH3_1, Pkinase_Tyr DDI of SH2 and Pkinase_Tyr
residues 33-33 of SH2 are in the interface residues 53-55 of SH2 are in the interface residues 56-58 of SH2 are in the interface residues 59-59 of SH2 are in the interface residues 63-68 of SH2 are in the interface residues 69-69 of SH2 are in the interface residues 71-71 of SH2 are in the interface residues 72-73 of SH2 are in the interface residues 75-75 of SH2 are in the interface residues 76-76 of SH2 are in the interface
Y_phosphatase DDI of SH2 and Y_phosphatase, SH2 DDI of SH2 and SH2, C2 DDI of SH2 and C2
residues 53-53 of SH2 are in the interface residues 54-55 of SH2 are in the interface residues 57-57 of SH2 are in the interface residues 62-62 of SH2 are in the interface residues 63-63 of SH2 are in the interface residues 64-64 of SH2 are in the interface residues 65-65 of SH2 are in the interface residues 66-66 of SH2 are in the interface residues 76-76 of SH2 are in the interface
Pkinase_Tyr DDI of SH2 and Pkinase_Tyr, fn3 DDI of SH2 and fn3, SH2 DDI of SH2 and SH2
residues 56-56 of SH2 are in the interface residues 67-67 of SH2 are in the interface
SH3_2 DDI of SH2 and SH3_2
residues 58-62 of SH2 are in the interface residues 66-66 of SH2 are in the interface residues 69-69 of SH2 are in the interface
C1_1 DDI of SH2 and C1_1
residues 68-69 of SH2 are in the interface residues 71-72 of SH2 are in the interface residues 75-75 of SH2 are in the interface
Pkinase_Tyr DDI of SH2 and Pkinase_Tyr
residues 73-73 of SH2 are in the interface residues 77-77 of SH2 are in the interface
LIG_SH2_SRC (Y[QDEVAIL][DENPYHI][IPVGAHS], from ELM) DMI of SH2 and LIG_SH2_SRC

You can find this domain in

GO terms associated with this domain

The SH2 domain is found in the following PDB entries:

Network of interacting domains and motifs

Network for SH2, depth 1

thin line:interchain interaction onlybold line:intrachain interaction onlydashed line:both interchain and intrachain interaction
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by molecular_function (GO term)
by biological_process (GO term)
by cellular_component (GO term)