The database of three-dimensional interacting domains (3did) is a collection of high-resolution three-dimensional structural templates for domain-domain interactions. It contains templates for interactions between two globular domains as well as novel domain-peptide interactions, derived using a recently published method from our lab.

Start by searching a domain or a motif in the search box below. If you need help visit our help page to discover how to get started. The complete contents of the database are also available for download.

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Pfam version35.0
PDB version2022_01
Domain-domain interactions15983
Motifs in interactions of known 3D structure1171

When referring to 3did, please cite:

Roberto Mosca, Arnaud Ceol, Amelie Stein, Roger Olivella & Patrick Aloy, 3did: a catalogue of domain-based interactions of known three-dimensional structure, Nucleic Acids Research 2014, 42(D1):D374-D379, doi:10.1093/nar/gkt887